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  What study type is considered at the highest rung of the evidence-based pyramid? 

  The highest rung on the evidence-based pyramid is the meta-analysis tier. Meta-analysis is a group of systematic reviews of multiple studies to find and compare the absolute best evidence available for a specific condition, population, or intervention. There is a precise, systematic methodology to research, choose, review, and evaluate the studies to include them in the meta-analysis (Tracy, et al., 2023). It gains the top tier of the evidence-based pyramid because meta-analysis yields the strongest level of evidence after all these systematic reviews (Melnyk & Fineoout-Overholt, 2019). These specific meta-analysis studies then present a summary of the current best evidence available for the area of interest. The meta-analyses can then guide clinicians to make evidence-based decisions for the treatment of their patients.

References: 

Melnyk, B. M., Fineout-Overholt, E. (2019). Evidence-Based Practice in Nursing and Healthcare (4th ed.). Wolters Kluwer

Tracy, M. F., O’Grady, E. T., & Phillips, S. J. (2023). Hamric & Hanson’s Advanced Practice Nursing: An Integrative Approach (7th ed.). Amsterdam: Elsevier.   

Cancer Treatment Options

 Mrs. Williams is a 27-year-old female diagnosed with breast cancer. She is currently in pharmacy school. She does not have children, but hopes to have them someday. She has been tested and has a genetic predisposition for this disease.

  • What treatment options does she have?
  • What are the advantages and disadvantages of those treatment options?
  • What would you tell Mrs. Williams if she decided to refuse treatment?
  • Mrs. Williams really wants to have children before she starts treatment. What would you educate her about? Why? 

* At least two pages with reference

If you refer to any outside sources or reference materials, be sure to provide proper attribution and/or citation.

Discussion 250 words. Make sure you provide 2 references and utilize APA style.. . Discussion Rubric

Many organizations provide educational materials about osteoporosis, physical activity, and other topics pertinent to health promotion for musculoskeletal wellness. Some materials are available in Spanish and other languages, and many of these materials are free.

From the list below select on organization and an intervention that you could implement in your current place of work to promote health development of your patient/client population. State reasons why and the EBP behind your selection.

America on the Move Foundation


https://aom3.americaonthemove.org

American Cancer Society


www/cancer.org

American Heart Association


www.heart.org

Arthritis Foundation


www.arthritis.org

National Institute of Arthritis and Musculoskeletal and Skin Diseases


www.niams.nih.gov

National Cancer Institute


www.cancer.gov

National Osteoporosis Foundation


www.nof.org

Please note the grading rubric for the discussion board.

As a reminder, all discussion posts must be a minimum of 250 words, references must be cited in APA format 7th Edition and must include a minimum of 2 scholarly resources published within the past 5 years.

Introduction and quality of discussion’s Argument

60% of total result

Objectivity of Tone, overall quality & Review of Literature in APA 6th format within past 7 years

10% of total result

Grammar / Writing Skills

7% of total result

nutrition

Nutrition plays a vital role in a person's overall health and well-being. Not getting enough of the recommended

nutrients over the long-term can lead to malnutrition which often results in disease and illness.

In a 3-page paper, written in APA format using proper spelling/grammar, address the following:

1. Define malnutrition and identify a specific disease that can result from it.

2. Perform library research about the selected disease, and explain its physiological effects on a

person's body.

3. Describe the relationship between specific foods/nutrients and the disease. Use the questions

below to guide your response.

4. Does research indicate that a lack of specific foods/nutrients increase a person's chance of

contracting the disease?

5. Are there specific foods/nutrients that should be avoided by an individual afflicted with the

disease?

6. How do specific foods/nutrients work physiologically within the body to help combat the

disease?

7. Evaluate nutritional recommendations to help combat the disease.

8. Cite at least 3 credible references and present the resources in APA format on the References

page.

9.

Informatics in healthcare

Assistance with an upcoming assessment

SEARCHING DATABASES

SEARCHING DATABASES

When you decide to purchase a new car, you first decide what is important to you. If mileage and dependability are the important factors, you will search for data focused more on these factors and less on color options and sound systems.

The same holds true when searching for research evidence to guide your clinical inquiry and professional decisions. Developing a formula for an answerable, researchable question that addresses your need will make the search process much more effective. One such formula is the PICO(T) format.

In this Discussion, you will transform a clinical inquiry into a searchable question in PICO(T) format, so you can search the electronic databases more effectively and efficiently. You will share this PICO(T) question and examine strategies you might use to increase the rigor and effectiveness of a database search on your PICO(T) question.

 
To Prepare:

· Review the Resources and identify a clinical issue of interest that can form the basis of a clinical inquiry.

· Review the materials offering guidance on using databases, performing keyword searches, and developing PICO(T) questions provided in the Resources.

· Based on the clinical issue of interest and using keywords related to the clinical issue of interest, search at least two different databases in the Walden Library to identify at least four relevant peer-reviewed articles related to your clinical issue of interest. You should not be using systematic reviews for this assignment, select original research articles.

· Review the Resources for guidance and develop a PICO(T) question of interest to you for further study. It is suggested that an Intervention-type PICOT question be developed as these seem to work best for this course. 

*Library tip

Walden Library recommends starting your search 
broadly with one concept or search word and adding more elements one at a time. Depending on your topic, the evidence will not necessarily address 
all the aspects of your PICO(T) question in one article. Select the most important concepts to search and find the best evidence available, even if that means assembling evidence from multiple articles.

·
Nursing Research PageLinks to an external site. – databases and resources specifically for Nursing

· Evidence-Based Practice guide: 
Evidence TypesLinks to an external site.

·
Nursing and Health research videosLinks to an external site., including a 15-minute introduction

·
Get HelpLinks to an external site. page, including 
Ask a LibrarianLinks to an external site. service

Quick Answers:

·
How do I find an article that reports on research that uses a specific methodology?Links to an external site.

·
How do I find original or primary research that analyzes empirical data?Links to an external site.

·
What is the Find at Walden button?Links to an external site.

Post a brief description of your clinical issue of interest. This clinical issue will remain the same for the entire course and will be the basis for the development of your PICOT question. Describe your search results in terms of the number of articles returned on original research and how this changed as you added search terms using your Boolean operators. Finally, explain strategies you might make to increase the rigor and effectiveness of a database search on your PICO(T) question. Be specific and provide examples.

Nursing Assignment Golden Age and Macromolecules

Golden Age of Microbiology: Use the given active learning template (ALT) to connect Scientists with their discoveries in 1-2 sentences. (Slide 1; 2.5 points)

Carolus Linnaeus

Antoni van Leeuwenhoek

Alexander Fleming

Joseph Lister

Ignaz Semmelweis

Robert Koch:
(Slide 2; 3 points)

Summary of Key Work:

Organisms Studied:

Other Findings:

Postulates:

Louis Pasteur:
S-shaped Flask experiment
(Slide 3; 2 points)

Hypothesis:

Experimental Design:

Results:

Conclusion:

Note for students: Macromolecules is a review from prior courses. This topic may or may not be covered in-class or online. You may use your textbook or books from prior courses for this ALT. (Slide 4; 2.5 points)

Complete the following table by describing the terms in1-2 sentences with their function and examples

Carbohydrates Functions and Examples
Monosaccharides
Disaccharides
Polysaccharides
Lipids Functions and Examples
Triglycerides
Phospholipids
Level of protein structure Structural organization
Primary  
 
Secondary  
 
Tertiary  
 
Quaternary  
 

Complete the following Table by adding information on bonds that participate in creating certain level of protein structure and if biological activity is present in that level of structure (Slide 5; 2 points)

Give an example of a disease that occurs due to errors in protein folding: ___________________________________

Type of NA Composition of the nucleotide Location, Function and types Structure and sugars
DNA
 
     
RNA
 
     

The two types of Nucleic acids ________________ and ______________

Role of ATP _________________________________________________________

Complete the following table about the composition, structure and functions of Nucleic acids (NA).

(Slide 6; 3 points)

safety

please this policy is wrong rewrite a perfect policy

553 u 8

 

Margo is a 49-year-old divorced woman who works as a bank teller. She tells her primary care provider (PCP) that she feels tired all the time and that she is gaining weight because she has no interest in her usual exercise activities, and that she has been overeating, even though she is often not really hungry. She notices that she has difficulty falling asleep at night and awakens around 4 a.m. most mornings, without her alarm, and cannot go back to sleep even though she still feels tired. She finds little joy in her life but cannot pinpoint any particular concern or event causing this problem. The PCP asks Angela to fill out a Beck’s Depression Scale, which indicates she has moderate depression.

  • Choose a pharmacologic intervention for Margo.
  • Provide Margo with written education regarding her prescription. (Include what she should expect when first taking the drug, appropriate activity warnings, when to expect improvement, side effects she may experience, and anything she should report to the provider).

instructions: It is a discussion post, one page to one page and a half is long enough. APA format. must have 3 references please.

Identify Health Trends within Counties

How do we identify health Trends?