What positive impact has the use of the stem cell treatment in patients with autoimmune diseases?
[Title]-Stem cell treatment and the positive impact on autoimmune diseases.
Research Question-What positive impact has the use of the stem cell treatment in patients with autoimmune diseases?
Objectives of the project.
1. To investigate the use of stem cell treatment in autoimmune diseases.
2. To demonstrate the positive impact of using stem cells to treat autoimmune diseases.
3. To present through a systematic review of the literature therapeutic options with stem cells that have the ability to successfully treat patients with autoimmune diseases.
Theoretical Framework– La teoría de la consecución de objetivos desarrollada por Imogene King.
My job no needed PICOT question due to be a literature review.
My References-I Needs more references
Ahmed, Z., Imdad, A., Connelly, J. A., & Acra, S. (2019). Autoimmune Enteropathy: An Updated Review with Special Focus on Stem Cell Transplant Therapy. Digestive Diseases & Sciences, 64(3), 643–654. https://doi-org.librarylogin-cupey.uagm.edu/10.1007/s10620-018-5364-1
Snowden, J. A., Sharrack, B., Akil, M., Kiely, D. G., Lobo, A., Kazmi, M., Muraro, P. A., & Lindsay, J. O. (2018). Autologous haematopoietic stem cell transplantation (aHSCT) for severe resistant autoimmune and inflammatory diseases — a guide for the generalist. Clinical Medicine, 18(4), 329–334. https://doi-org.librarylogin-cupey.uagm.edu/10.7861/clinmedicine.18-4-329
Ferreira Zombrilli, A., Leopoldo, V. C., Oliveira, M. C., Cirioli de Oliveira, M. de F., Ehmke Dolci, M., Merizio Martins Braga, F. T., & de Campos Pereira Silveira, R. C. (2019). Virtual learning object in hematopoietic stem cell transplantation for autoimmune diseases. Revista Brasileira de Enfermagem, 72(4), 994–1000. https://doi-org.librarylogin-cupey.uagm.edu/10.1590/0034-7167-2018-0669
Balassa, K., Danby, R., & Rocha, V. (2019). Haematopoietic stem cell transplants: principles and indications. British Journal of Hospital Medicine (17508460), 80(1), 33–39. https://doi-org.librarylogin cupey.uagm.edu/10.12968/hmed.2019.80.1.33
Van Laar, J. M., Naraghi, K., & Tyndall, A. (2015). Haematopoietic stem cell transplantation for poor-prognosis systemic sclerosis. Rheumatology, 54(12), 2126–2133. https://doi-org.librarylogin-cupey.uagm.edu/10.1093/rheumatology/kev117
Atkins, H., Freedman, M., Atkins, H. L., & Freedman, M. S. (2017). Five Questions Answered: A Review of Autologous Hematopoietic Stem Cell Transplantation for the Treatment of Multiple Sclerosis. Neurotherapeutics, 14(4), 888–893. https://doi-org.librarylogin-cupey.uagm.edu/10.1007/s13311-017-0564-5
Currò, D., Mancardi, G., & Currò, D. (2016). Autologous hematopoietic stem cell transplantation in multiple sclerosis: 20 years of experience. Neurological Sciences, 37(6), 857–865. https://doi-org.librarylogin-cupey.uagm.edu/10.1007/s10072-016-2564-3
Baharlou, R., Rashidi, N., Ahmadi-Vasmehjani, A., Khoubyari, M., Sheikh, M., & Erfanian, S. (2019). Immunomodulatory Effects of Human Adipose Tissue-derived Mesenchymal Stem Cells on T Cell Subsets in Patients with Rheumatoid Arthritis. Iranian Journal of Allergy, Asthma & Immunology, 18(1), 114–119.
Ferreira Zombrilli, A., Leopoldo, V. C., Oliveira, M. C., Cirioli de Oliveira, M. de F., Ehmke Dolci, M., Merizio Martins Braga, F. T., & de Campos Pereira Silveira, R. C. (2019). Virtual learning object in hematopoietic stem cell transplantation for autoimmune diseases. Revista Brasileira de Enfermagem, 72(4), 994–1000. https://doi-org.librarylogin-cupey.uagm.edu/10.1590/0034-7167-2018-0669
Snowden, J. A., Sharrack, B., Akil, M., Kiely, D. G., Lobo, A., Kazmi, M., Muraro, P. A., & Lindsay, J. O. (2018). Autologous haematopoietic stem cell transplantation (aHSCT) for severe resistant autoimmune and inflammatory diseases — a guide for the generalist. Clinical Medicine, 18(4), 329–334. https://doi-org.librarylogin-cupey.uagm.edu/10.7861/clinmedicine.18-4-329
Ahmed, Z., Imdad, A., Connelly, J. A., & Acra, S. (2019). Autoimmune Enteropathy: An Updated Review with Special Focus on Stem Cell Transplant Therapy. Digestive Diseases & Sciences, 64(3), 643–654. https://doi-org.librarylogin-cupey.uagm.edu/10.1007/s10620-018-5364-1
APA -Rebeiro, P., & Moore, J. (2016). The role of autologous haemopoietic stem cell transplantation in the treatment of autoimmune disorders. Internal medicine journal, 46(1), 17-28
APA- Snowden, J. A., Badoglio, M., Labopin, M., Giebel, S., McGrath, E., Marjanovic, Z., … & Kazmi, M. (2017). Evolution, trends, outcomes, and economics of hematopoietic stem cell transplantation in severe autoimmune diseases. Blood advances, 1(27), 2742-2755.
Xiaoxiao Lu, Xilian Wang, Hong Nian, Dan Yang & Ruihua Wei. Mesenchymal stem cells for treating autoimmune dacryoadenitis Stem Cell Research & Therapy, volume 8, Article number: 126 (2017)
How to write a Proposal
1. Literature review
2. Case study (You need a letter of approval from the patient and/or the provider, describe how you are handling confidentially of the information)
3. Pre and post-education (You may need to write a consent form, and you need a letter of approval from your organization)
Components of the Proposal
I. Title
II. Introduction
An introduction should announce your topic. You can start your introduction with a few sentences, which announce the topic of your paper and give an indication of the kind of research questions you will be asking. The first few sentences should act as an indication of a broader problem, which you will then focus on more closely in the rest of your introduction, leading to your specific research questions. The introduction should include the purpose of the project and the Methods.
III. The Problem
1. Research Question
The research question should be concise and closely focused. The research question might recall some of the key words established in the first few sentences and the title of your paper. You have to write the Question.
2. Objective or Objectives
Objectives must always be set after having formulated a good research question. After all, they are to explain the way in which such a question is going to be answered. Objectives are usually headed by infinitive verbs such as:
·
· To identify
· To establish
· To describe
· To determine
· To estimate
· To develop
· To compare
· To analyze
· To collect
3. You need to explain the contribution of the research to the topic and to the advanced nursing practice. Use references.
IV. Review of Literature.
The purpose is to offer an overview of the significant literature published on a topic:
1. identifies areas of prior scholarship
2. Describes the relationship of each source to the others that you have selected
3. Points the way forward for further research.
The literature review should include the following:
1. Objective of the literature review
2. Overview of the subject under consideration.
3. Particular position, those opposed, and those offering completely different arguments.
4. Discussion of both the distinctiveness of each source and its similarities with the others.
No less than 30 references (15 for NURS 502, and 15 for NURS 503).
No older than 2015.
Include a nursing theory or a conceptual model and describe it.
V. Methodology.
· Describe the design
· Identify the variable
· Describe the reliability and validity of the instrument
· Describe the population and the sample.
· Describe the steps to protect the rights of human according to IRB criteria.
· Discuss the procedure to complete the study.
VI. Data analysis.
4. Describe the data analysis according to the design and variables.
Addendum:
1. Copy of the proposal.
2. Copy of instruments.
3. Copy of consents.
4. IRB F01 (or F08).
5. CV
6. CITI training.
7. APA.
